Structural studies on Mycobacterial NudC reveal a class of zinc independent NADH pyrophosphatase
收藏DataCite Commons2025-04-27 更新2025-05-18 收录
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Non-tuberculous mycobacteria (NTM) have emerged as an increasing threat to public health, due to the extreme antibiotic resistance. NADH pyrophosphatase (NudC) was proposed involving in mycobacterial resistance to the first line anti-tubercular drug isoniazid (INH) or its analog ethionamide (ETH), by hydrolyzing their NAD modified active forms (NAD-INH and NAD-ETH).
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创建时间：
2024-12-09
