Top ranked GSEA annotation terms in SLEPR Analysis Result for Comparison of NGT vs DM2+IGT in human DM2 data.

Microarray data for human type 2 diabetes mellitus (DM2) study [23] was re-analyzed with SLEPR method to compare either NGT versus IGT+DM2 (IGT+DM2 as Exclusion/Background class in SLEPR). One-side MADe method was used in SLEPR for selection of highly expressed genes as sample-level differentiated genes in the comparison of NGT versus IGT+DM2. Two-side MADe method was also used for selection of highly and lowly expressed genes as sample-level differentiated genes, and similar result was obtained (see Table S4). 1000 permutations were performed. Combined_Ranking: Combined ranking scores for terms; Permutated_P_Val: p-value of terms derived from permutated data; FDR_q_Val: FDR of terms derived from permutated data (see Materials And Methods section for details).