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Crystal structure of Mcl1 with inhibitor 9

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Protein Data Bank Japan2024-03-13 更新2026-03-21 收录
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Crystal structure of Mcl1 with inhibitor 9 Descriptor: (4S,7aR,9aR,10S,11E,15R)-6'-chloro-10-hydroxy-15-methyl-3',4',7a,8,9,9a,10,13,14,15-decahydro-2'H,3H,5H-spiro[1,19-(ethanediylidene)-16lambda~6~-cyclobuta[i][1,4]oxazepino[3,4-f][1,2,7]thiadiazacyclohexadecine-4,1'-naphthalene]-16,16,18(7H,17H)-trione, Induced myeloid leukemia cell differentiation protein Mcl-1 Authors: Huang, X. Deposit date: 2019-04-26 Release date: 2019-05-15 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: AMG 176, a Selective MCL1 Inhibitor, Is Effective in Hematologic Cancer Models Alone and in Combination with Established Therapies. CANCER DISCOV, 8, 2018
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2019-04-26
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