BACE crystal structure with hydroxy pyrrolidine inhibitor
收藏Protein Data Bank Japan2024-10-16 更新2026-03-21 收录
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BACE crystal structure with hydroxy pyrrolidine inhibitor Descriptor: Beta-secretase 1, GLYCEROL, N-[(1R,2S)-1-[(2R,4R)-4-(cyclohexylmethoxy)pyrrolidin-2-yl]-3-(3,5-difluorophenyl)-1-hydroxypropan-2-yl]acetamide Authors: Timm, D.E. Deposit date: 2017-10-26 Release date: 2017-11-15 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.51 Å) Cite: Optimization of Hydroxyethylamine Transition State Isosteres as Aspartic Protease Inhibitors by Exploiting Conformational Preferences. J. Med. Chem., 60, 2017
创建时间：
2017-10-26
