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Methylation mValues

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下载链接:
https://figshare.com/articles/dataset/Methylation_mValues/21257694
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资源简介:
M-values of frontal methylation data from the RiMod-FTD resource (https://www.biorxiv.org/content/10.1101/2020.12.01.405894v4). Data was processed as follows: The Infinium MethylationEPIC BeadChip, which consists of 866,091 CpG locations, data was analyzed using the minfi R package. We removed all sites with a detection P-value above 0.01, on sex chromosomes and with single nucleotide polymorphisms (SNPs), leaving 810,290 loci for analysis. Data normalization was done using stratified quantile normalization. Sites with a standard deviation below 0.1 were considered uninformative and filtered out, leaving 170,595 sites that were used to perform a principal component analysis.
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2022-10-22
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