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Crystal structure of human ClpP in complex with ZG111

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Protein Data Bank Japan2023-11-29 更新2026-05-23 收录
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Crystal structure of human ClpP in complex with ZG111 Descriptor: (6S,9aS)-N-[(4-bromophenyl)methyl]-6-[(2S)-butan-2-yl]-8-(naphthalen-1-ylmethyl)-4,7-bis(oxidanylidene)-3,6,9,9a-tetrahydro-2H-pyrazino[1,2-a]pyrimidine-1-carboxamide, ATP-dependent Clp protease proteolytic subunit, mitochondrial, ... Authors: Wang, P.Y, Gan, J.H, Yang, C.-G. Deposit date: 2021-10-15 Release date: 2022-06-08 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.552 Å) Cite: Aberrant human ClpP activation disturbs mitochondrial proteome homeostasis to suppress pancreatic ductal adenocarcinoma. Cell Chem Biol, 29, 2022

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2021-10-15
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