Sequential Cu(I)/Pd(0)-Catalyzed Multicomponent Coupling and Annulation Protocol for the Synthesis of Indenoisoquinolines
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Copper-catalyzed coupling of imines, vinylstannanes, or alkynes and o-bromoaroyl chlorides followed by Pd(0)-catalyzed annulations afforded indenoisoquinolines. Protocols requiring minimal purifications were developed, providing new methods for the construction of combinatorial libraries.
创建时间：
2009-02-19
