Comprehensive in vitro drug testing of small molecule inhibitor on nasopharyngeal carcinoma cell lines from transcription to protein level regarding cell cycle, proliferation, cell death and clonogeni
Flavonoids represent a potential source of new antitrypanosomatidic leads. Starting from a library of natural products, we combined target-based screening on pteridine reductase 1 with phenotypic scre
Bifunctional dihydrofolate reductase–thymidylate synthase (DHFR-TS) is a chemically and genetically validated target in African trypanosomes, causative agents of sleeping sickness in humans and nagana
