Supporting Information S1 - Clinical Characteristics of Children with Autism Spectrum Disorder and Co-Occurring Epilepsy

Supporting Tables. Table S1 Epilepsy Diagnosis by Age among Individuals with Autism Spectrum Disorder, Genetic Collaborative Samples. The prevalence of epilepsy was significantly higher in older children in all of the genetic collaborative samples. Table S2 Epilepsy Diagnosis by Gender among Individuals with Autism Spectrum Disorder, Genetic Collaborative Samples. The prevalence of epilepsy was higher in females with ASD in all of the genetic collaborative samples, but this difference only reached statistical significance in the AGRE sample. Table S3 Epilepsy Diagnosis by History of Developmental Regression among Individuals with Autism Spectrum Disorder, Genetic Collaborative Samples. The prevalence of epilepsy was higher in individuals with a history of developmental regression in all of the genetic collaborative samples. Table S4 Epilepsy Diagnosis by Language among Individuals with Autism Spectrum Disorder, Genetic Collaborative Samples. The prevalence of epilepsy was significantly higher in individuals with fewer than 5 words in all of the genetic collaborative samples. Table S5 Epilepsy Diagnosis by Cognitive Ability among Individuals with Autism Spectrum Disorder, Genetic Collaborative Samples. Individuals with epilepsy had significantly lower cognitive ability in all of the genetic collaborative samples. Table S6 Epilepsy Diagnosis by Intellectual Disability among Individuals with Autism Spectrum Disorder, Genetic Collaborative Samples. The prevalence of epilepsy was higher in individuals with intellectual disability in all of the genetic collaborative samples. Table S7 Epilepsy Diagnosis by Adaptive Functioning among Individuals with Autism Spectrum Disorder, Genetic Collaborative Samples. Individuals with epilepsy had significantly lower adaptive functioning in all of the genetic collaborative samples. Table S8 Epilepsy Diagnosis by Autism Severity among Individuals with Autism Spectrum Disorder, Genetic Collaborative Samples. Individuals with epilepsy had higher mean ADOS Calibrated Severity scores in all of the genetic collaborative samples. Table S9 Logistic Regression Modeling the Odds of an Epilepsy Diagnosis by Demographic and Clinical Characteristics, Individual Genetic Collaborative Samples. Logistic regression model findings were similar in participants of the individual genetic collaborative samples to the results from the combined sample. Table S10 Cross-Validation of Parent Report Epilepsy Diagnosis on the ADI-R with Report of Non-Febrile Seizures based on Medical History, Subset of Genetic Collaborative Study Participants (n = 2,525). There was good agreement between parent report of epilepsy diagnosis on the ADI-R and medical history.
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