The datasets stored in TICCom

This database provided five datasets. The first dataset contained experimentally verified tumor-immune cell interactions which included interacting gene symbols, cell types, interaction types, cancer types, species and other detailed information. The second dataset consisted of integrated ligand-receptor interactions including ligands, receptors, functions and sources. The third dataset presented significant interacting experimentally verified tumor-immune cell interactions inferred via Interaction Intensity module based on cancer types from TCGA (https://portal.gdc.cancer.gov/), ICGC (https://dcc.icgc.org/) and EMBL-EBI Expression Atlas (https://www.ebi.ac.uk/gxa/home). The fourth dataset contained significant interacting integrated ligand-receptor interactions predicted by TItalk based on cancer types from TCGA, ICGC and EMBL-EBI Expression Atlas. The fifth dataset consisted of predicted tumor-immune cell interactions inferred by five algorithms based on 32 scRNA-seq datasets and union of ligand-receptor interactions. These datasets can be downloaded from the Download module in TICCom.