Transcriptomic changes in response to 5/6 or 1/3 nephrectomy

We report the changes in kidney mRNA abundance in response to 5/6 nephrectomy or 1/3 nephrectomy surgery when compared to sham operated controls. Overall design: Ten week old male Sprague Dawley rats were subjected to the excision model of 5/6 nephrectomy (5/6Nx; right kidney + 2/3 of left kidney), 1/3 nephrectomy (1/3Nx; 2/3 of left kidney excised), or sham surgery (left kidney). Left kidney tissue was collected 6 weeks later for mRNA sequencing.