Pyridoxal 5’-phosphate (PLP) functions as a cofactor for hundreds of different enzymes that are crucial to the survival of microorganisms. PLP-dependent enzymes have been extensively characterized and
Color scale indicates drug potency: darker blue = more potent, lighter blue = less potent. Anti-amoebic activity classified based on EC50 value as: Very high (0.001–0.999 μM), High (1.000–4.999 μM), M