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Mircoarray data-LncRNA Analysis of Lung Tissues after hUC-MSCandFTY720 Treatment of Lipopolysaccharide-induced Acute Lung Injury in Mice

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DataCite Commons2020-08-28 更新2024-07-27 收录
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https://figshare.com/articles/LncRNA_Analysis_of_Lung_Tissues_after_hUC-MSCandFTY720_Treatment_of_Lipopolysaccharide-induced_Acute_Lung_Injury_in_Mice/7334171
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<b>Methods</b>. We built a lipopolysaccharide (LPS)-induced ALI model in mice. After treatment with hUC-MSCs, FTY720, or a combination of hUC-MSCs and FTY207, the lung inflammatory response was apparently attenuated. To understand the mechanism underlying MSC treatment of ALI at the genetic level, significant differentially expressed long non-coding RNAs (lncRNAs) between the treatment and model groups were analyzed using microarray technology. Moreover, genetic gene prediction, gene ontology (GO) analysis, pathway analysis, and transcription factor (TF) prediction were carried out. The research procedures were approved by the Affiliated Hospital of Military Medical Science Scientific Research Ethics Committee.(IRB Approval number: ky-2015-3-7)
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figshare
创建时间:
2018-11-13
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