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TATA-Binding Protein Variants that Bypass the Requirement for Mot1 In Vivo

Alliance of Genome Resources2026-08-01 收录

转录调控机制

TBP变体功能

数据链接：

https://www.yeastgenome.org/dataset/GSE12371 数据链接链接失效反馈

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资源简介：

Mot1 is an essential TATA-binding protein (TBP)-associated factor and Snf2/Swi2 ATPase that both represses and activates transcription

应用场景：

基因治疗研究

转录调控机制

X-linked adrenoleukodystrophy (X-ALD) is a peroxisomal disorder caused by mutations in the ABCD1 gene that encodes the peroxisomal ATP-binding cassette (ABC) transporter subfamily D member 1 protein (

NIAID Data Ecosystem30

Structure of transcription regulator CcpA in its DNA-free state

蛋白质结构解析

转录调控机制

Structure of transcription regulator CcpA in its DNA-free state

NIAID Data Ecosystem20

BHLHE40 is key hypoxia-induced transcriptional repressor in beta cells. BHLHE40 is key hypoxia-induced transcriptional repressor in beta cells

细胞缺氧反应

转录调控机制

To assess the impact of hypoxia on global gene expression of beta cells, we performed bulk RNA-seq on mouse islets, human islets and MIN6 cells. Bhlhe40 was transcriptional repressor which was highly

NIAID Data Ecosystem20

Co-regulated gene expression downstream of a single transcription factor controls the acquisition of corticospinal motor neuron identity

神经元亚型

转录调控机制

The neocortex contains an unparalleled diversity of neuronal subtypes responsible for complex behavior. Each cortical neuron has distinct traits, which are developmentally acquired under the control o

NIAID Data Ecosystem20

Genome-wide analysis of MEF2-dependent gene expression in human NSCs. Homo sapiens

转录调控机制

干细胞基因功能

Redox-mediated posttranslational modifications represent a molecular switch that controls major mechanisms of cell function. Nitric oxide (NO) can mediate redox reactions via S-nitrosylation, represen

NIAID Data Ecosystem20

TATA-Binding Protein Variants that Bypass the Requirement for Mot1 In Vivo

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