Population genetic parameters partition Anopheles coluzzii and A. gambiae candidate genes into discrete clusters.

For 26 genes sequenced from wild A. coluzzii and A. gambiae mosquitoes from Burkina Faso, scatterplot indicates the log-ratio of nucleotide diversity, π, for A. coluzzii / A. gambiae (x-axis) an Fig 1. Population genetic parameters partition Anopheles coluzzii and A. gambiae candidate genes into discrete clusters. For 26 genes sequenced from wild A. coluzzii and A. gambiae mosquitoes from Burkina Faso, scatterplot indicates the log-ratio of nucleotide diversity, π, for A. coluzzii / A. gambiae (x-axis) and pairwise Fst between A. coluzzii and A. gambiae (y-axis). Negative values for log-ratio of π indicate greater diversity in A. gambiae positive values greater diversity in A. coluzzii, and a value of 0 indicates no difference in nucleotide diversity between A. coluzzii and A. gambiae. The names of genes subsequently tested by functional analyses are shown, for others see S1 Table. Dashed ovals indicate unbiased hierarchical clusters identified by the method of Ward based on minimized within-cluster variance, with optimal number of clusters k = 3 as determined by the Krzanowski-Lai index (S1 Fig), stars indicate cluster centroids.d pairwise Fst between A. coluzzii and A. gambiae (y-axis). Negative values for log-ratio of π indicate greater diversity in A. gambiae positive values greater diversity in A. coluzzii, and a value of 0 indicates no difference in nucleotide diversity between A. coluzzii and A. gambiae. The names of genes subsequently tested by functional analyses are shown, for others see S1 Table. Dashed ovals indicate unbiased hierarchical clusters identified by the method of Ward based on minimized within-cluster variance, with optimal number of clusters k = 3 as determined by the Krzanowski-Lai index (S1 Fig), stars indicate cluster centroids.