TERT Promoter DNA methylation landscape in human cancer cell lines and tumors

We assessed methylation landscape near the human TERT promoter in various normal samples and tumor samples, to assess the unique hypermethylation phenotype that exist in human cancers Overall design: DNA from various tissues (i.e. human cancer cell lines, normal cells, and tumor tissue) were extracted and analyzed with bisulfite targeted sequencing of the TERT promoter