Banerjee2008 - Immunotherapy with interleukin-2: A study based on mathematical modeling
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资源简介：
IMMUNOTHERAPY WITH INTERLEUKIN-2: A STUDY BASED ON
MATHEMATICAL MODELING
S ANDIP B ANERJEE
Indian Institute of Technology and Science Rooorkee (IITR)
Roorkee 247667, Uttarakhand, India
e-mail: sandofma@iitr.ernet.in
The role of interleukin-2 (IL-2) in tumor dynamics is illustrated through mathematical modeling, using delay differential
equations with a discrete time delay (a modified version of the Kirshner-Panetta model). Theoretical analysis gives an
expression for the discrete time delay and the length of the time delay to preserve stability. Numerical analysis shows that
interleukin-2 alone can cause the tumor cell population to regress.
Keywords: effector cells, tumor cells, interleukin-2, discrete time delay.
创建时间：
2020-01-13
