Crystal Structure of the First Bromodomain of Human BRD4 in Complex With Cyclic Vinylogous Amide Inhibitor MS402
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Crystal Structure of the First Bromodomain of Human BRD4 in Complex With Cyclic Vinylogous Amide Inhibitor MS402 Descriptor: 3-chloranyl-~{N}-(4-methoxyphenyl)-4-[(2-methyl-3-oxidanylidene-cyclopenten-1-yl)amino]benzamide, Bromodomain-containing protein 4 Authors: Plotnikov, A.N, Joshua, j, Zhou, M.-M. Deposit date: 2017-01-24 Release date: 2017-03-22 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.5 Å) Cite: BET N-terminal bromodomain inhibition selectively blocks Th17 cell differentiation and ameliorates colitis in mice. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
创建时间：
2017-01-24
