Fusion genes are potent driver mutations in cancer. In this study, we delineate the fusion gene landscape in a consecutive series of 195 pediatric B-cell precursor acute lymphoblastic leukemia (BCP AL

NIAID Data Ecosystem30

A KMT2A-AFF1 gene regulatory network highlights the role of core transcription factors and reveals the regulatory logic of key downstream target genes.. A KMT2A-AFF1 gene regulatory network highlights the role of core transcription factors and reveals the regulatory logic of key downstream target genes.

白血病融合基因

转录调控网络

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem20

Supplementary Material for: Truncated RUNX1 Generated by the Fusion of RUNX1 to Antisense GRIK2 via a Cryptic Chromosome Translocation Enhances Sensitivity to Granulocyte Colony-Stimulating Factor

白血病融合基因

RUNX1

Fusions of the Runt-related transcription factor 1 ( RUNX1 ) with different partner genes have been associated with various hematological disorders. Interestingly, the C-terminally truncated form of

NIAID Data Ecosystem40

Fusion transcripts

白血病融合基因

RNA测序分析

In this study we aimed to identify fusion transcripts by RNAseq in acute myeloid leukemia (AML) without recurrent genetic abnormalities and correlate them with clinical and phenotypic data. For this p

NIAID Data Ecosystem20

Additional file 4 of MLL-AF4 and a murinized pSer-variant thereof are turning on the nucleolar stress pathway

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