Fusions of the Runt-related transcription factor 1 ( RUNX1 ) with different partner genes have been associated with various hematological disorders. Interestingly, the C-terminally truncated form of
Myriad of craniofacial disorders are caused by heterozygous mutations in general regulators of housekeeping cellular functions such as ribosome biogenesis. While it is understood that many of these hi
Gene expression profiles in Ba/F3 cells expressing ETV6-PDGFRB, FIP1L1-PDGFRA or a control vector, treated or not with imatinib (Glivec) Overall design: Ba/F3 cells expressing FIP1L1-PDGFRA or ETV6-PD