Identification of potential new GraR regulon members by in silico genome scanning.

aGene names correspond to the annotation of the S. aureus NCTC 8325 genome sequence [69]. Only the first gene is indicated for operons.bPositions of the inverted repeats of the potential GraR-binding sites are indicated for the given DNA strand with respect to the translation initiation codon.cKnown and putative functions for each regulon member based on genome annotations are indicated. Based on these predictions, the potential regulon members were divided in six categories (antimicrobial resistance, transport, cell envelope modification, oxidoreduction processes, other functions and unknown function).*Indicates genes known or predicted to be controlled by the WalKR TCS [44], [46].