tRFtarget

tRFtarget is a relational database respect to the computational predicted binding interactions between tRFs and target transcripts for multiple organisms based on the state-of-the-art prediction tools RNAhybrid and IntaRNA.The database can provide detailed information about the binding interactions as well as an illustration of the interaction sequences. Furthermore, the database can be also searched by tRF ID, gene or transcript to get a comprehensive transcriptome-wide overview of tRF-target interactions.The database also provides experimental evidence of the predicted tRF-mRNA interactions and functional studies on tRFs based on manually curated publications. The experimental evidence are classed into 2 categories: gene level evidence and site level evidence.tRFtarget是一款关系型数据库，收录了基于前沿预测工具RNAhybrid与IntaRNA计算预测得到的、覆盖多种生物的tRF（transfer RNA-derived fragments）与靶标转录本间的结合互作数据。该数据库可提供结合互作的详细信息，以及互作序列的可视化图示。此外，用户可通过tRF ID、基因或转录本进行检索，以获取全转录组范围内tRF-靶标互作的综合概览。该数据库还提供了预测得到的tRF-mRNA互作的实验证据，以及基于人工审校文献开展的tRF功能研究相关数据。上述实验证据分为两类：基因水平证据与位点水平证据。

搜集汇总

背景与挑战

背景概述

tRFtarget是一个基于RNAhybrid和IntaRNA工具预测多个生物体中tRF与目标转录本结合相互作用的数据库。它提供结合相互作用的详细信息、序列图示，并支持通过tRF ID、基因或转录本进行搜索，以获取转录组范围内的交互概览。此外，数据库还整合了基于人工整理文献的实验证据，并允许用户通过在线服务上传自定义序列进行预测。