Structure of CDC2-Like Kinase 2 (CLK2) in Complex with Compound T-025 [N2-methyl-N4-(pyrimidin-2-ylmethyl)-5-(quinolin-6-yl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine]
收藏Protein Data Bank Japan2024-03-06 更新2026-03-21 收录
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Structure of CDC2-Like Kinase 2 (CLK2) in Complex with Compound T-025 [N2-methyl-N4-(pyrimidin-2-ylmethyl)-5-(quinolin-6-yl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine] Descriptor: Dual specificity protein kinase CLK2, N~2~-methyl-N~4~-[(pyrimidin-2-yl)methyl]-5-(quinolin-6-yl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine Authors: Klein, M.G, Tjhen, R. Deposit date: 2017-01-31 Release date: 2018-05-09 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.92 Å) Cite: A novel CLK inhibitor exhibits anti-tumor efficacies via modulating pre-mRNA splicing and targeting a MYC-dependent vulnerability Embo Mol Med, 2018
创建时间：
2017-01-31
