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Dendritic silica with carbon dots and gold nanoclusters for dual nanozymes

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科学数据银行2023-09-27 更新2026-04-23 收录
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Many biochemical processes are accomplished by multiple enzymes, so it is important to develop nanocomposite microspheres with multiple enzyme mimetic ability. Here, well-designed nanozyme engineering (termed dSCS-Au NPs) was established for dual nanozymes with dendritic silica spheres (dSs) used as a carrier. The carbon dots (C-dots) were covalently immobilized into the interior surface of amino-terminated dSs, while gold nanoclusters (Au NCs) were linked to the surface of the dSs through activating agents of EDC/NHS. The dSCS-Au NPs exhibited excellent compatibility for two nanozymes, maintaining the superoxide dismutase (SOD)-like activity of C-dots and improving the horseradish peroxidase (HRP)-like activity of Au NCs. In addition, the HRP-like activity of dSCS-Au NPs could be regulated by changing the amount of loading of Au NCs. It has promising applications in biocatalysis with multiple enzyme reactions in the future.
提供机构:
Lirong Zhao; Department of Interventional Radiology, Shenzhen People's Hospital, Second Clinical Medical College of Jinan University, First Affiliated Hospital of Southern University of Science and Technology; Laboratory of Controllable Preparation and Application of Nanomaterials, CAS Key Laboratory of Cryogenics, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences
创建时间:
2022-10-27
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