Inhibitory effects of the selected title compounds against DNA gyrase.

NIAID Data Ecosystem10

Identifying the catalytic residue of the ATPase reaction of DNA gyrase.

We propose a mechanism for the hydrolysis of ATP by the DNA gyrase B protein in which Glu42 acts as a general base and His38 has a role in aligning and polarizing the glutamate residue. We have tested

PubMed Central1993-12-01 更新00

Relative inhibitory effects of selected known and newly tested compounds against ADC.[a]

[a]The measurements were performed using 1 mM L-aspartate, 3 µM ADC, and 1 mM compound (potential inhibitor) in D2O at 25°C.[b]The conversion percentage corresponds to the product formed by integratio

Figshare2015-12-02 更新00