Supplementary materials: Acute effects of resistance exercise with blood flow restriction on cardiovascular response: a meta-analysis

<b>These are peer-reviewed supplementary materials for the article '</b><b>Acute effects of resistance exercise with </b><b>blood flow restriction on cardiovascular </b><b>response: a meta-analysis</b><b>' published in the</b><b> </b><b><i>Journal of Comparative Effectiveness Research</i></b><b>.</b><b>Appendix</b> <b>1: </b>Search strategies<b>Appendix 2: </b>Funnel plot analysis<b>Appendix 3: </b>Table 1. Methodological quality of eligible studies, PEDRo scale.<b>Appendix</b> <b>4: </b>Assessment of the quality of evidence through the grade system<b>Appendix</b> <b>5: </b>Exploratory analysis of the BFR and resistance training<b>Aim: </b>To compare the acute effects of low-load resistance training associated with blood flow restriction (LLRT-BFR) with low-load resistance training (LLRT) and high-load resistance training (HLRT) on cardiovascular outcomes in healthy individuals. <b>Methods:</b> This review was registered and the studies were selected using seven databases. Randomized controlled clinical trials were included that evaluated LLRT-BFR compared with LLRT and HLRT in young individuals for the cardiovascular outcomes. <b>Results:</b> 19 studies were included. In the comparison of LLRT-BFR with HLRT, there were significant differences for cardiac output and heart rate – with reduced values and in favor of LLRT-BFR. <b>Conclusion:</b> There are no greater acute effects of the addition of blood flow restriction, with the exception of the reduction in cardiac output and heart rate for LLRT-BFR compared with HLRT.