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Glycogen synthase kinase-3 is essential for Treg development and homeostasis

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE277605
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Study of the effects of inducible deletion of Gsk3a and Gsk3b in Tregs. Foxp3-ERT2-cre-eGFP x Gsk3a/b x tdTomato-Ai9 and Foxp3-ERT2-cre-eGFP x tdTomato-Ai9 mice were treated with tamoxifen, and 14 days later tdTomato+ cells were sorted (n=4 mice per condition), labelled with HTO antibodies, and combined into 2 pools (of 2 WT and 2 KO mice each) for 10x single cell RNA sequencing.
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2025-09-03
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