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LSD1 Corepressor Rcor2 Orchestrates Neurogenesis in the Developing Mouse Brain [RNA-Seq]

Alliance of Genome Resources2026-08-01 收录

神经发生转录组

发育阶段基因调控

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http://www.informatics.jax.org/gxd/htexp_index/summary?arrayExpressID=GSE75038 数据链接链接失效反馈

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RNA-seq analysis of Rcor2fl/fl and Rcor2cko embryonic cortex. we dissected VZ-SVZ regions of Rcor2fl/fl and Rcor2cko cortex at E13.5 and E15.5 for RNA-seq respectively.

应用场景：

发育阶段基因调控

癌症分子机制

Whether a gene involved in distinct tissue or cell functions exerts a core of common molecular activities is a relevant topic in evolutionary, developmental, and pathological perspectives. Here, we ad

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CTCF-dependent insulation of Hoxb13 and the heterochronic control of tail length [CUT&RUN]

CTCF转录因子

发育阶段基因调控

In mammals, tail length is controlled by several genetic determinants, amongst which Hox13 genes located at the posterior extremities of Hox clusters, whose main function are to terminate the extensio

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Developmental ablation of Id1 and Id3 genes in the vasculature leads to postnatal cardiac phenotypes

发育阶段基因调控

扩张型心肌病分子机制

Rationale: The Id1 and Id3 genes play major roles during cardiac development, despite their expression being confined to non-myocardial layers (endocardium – endothelium - epicardium). We previously d

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Cooperative genetic networks drive embryonic stem cell transition from naïve to formative pluripotency. Cooperative genetic networks drive embryonic stem cell transition from naïve to formative pluripotency

胚胎干细胞多能性

发育阶段基因调控

In the mammalian embryo, epiblast cells must exit the naïve state and acquire formative pluripotency. This cell state transition is recapitulated by mouse embryonic stem cells (ESCs), which undergo pl

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mRNA sequencing time course of C. elegans samples at time point 1 hours until time point 24 hours at 25 degree [blmp-1(tm548) mutant]

基因表达振荡

发育阶段基因调控

We find gene expression oscillations which arise after a time lag of around 5 hours. Molecular oscillators can organize gene expression during development both temporally and spatially. In C. elegans,

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LSD1 Corepressor Rcor2 Orchestrates Neurogenesis in the Developing Mouse Brain [RNA-Seq]

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