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Human and rat skeletal muscle single-nuclei multi-omic integrative analyses nominate causal cell types, regulatory elements, and SNPs for complex traits

NIAID Data Ecosystem2026-03-13 收录

单细胞多组学

遗传关联分析

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE178735 数据链接链接失效反馈

官方服务：

资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2021-12-01

单细胞多组学

甲基化与转录组关联分析

Single-cell genomics and single-cell transcriptomics have recently emerged as powerful tools to study the biology of single cells at a genome-wide scale. Here we describe a method that allows the inte

NIAID Data Ecosystem20

Single cell multiomics guided mechanistic understanding of Fontan-associated liver disease

单细胞多组学

先天性心脏病继发肝病

Liver biopsy samples were from patients with Fontan circulation (FC) and healthy patients undergoing resection or transplant for hepatoblastoma. We used snRNA-ATAC-seq to generate the transcriptomic

NIAID Data Ecosystem00

Single-nucleus multiomics of murine gonads reveals gene-regulatory networks underlying sex determination. Single-nucleus multiomics of murine gonads reveals gene-regulatory networks underlying sex determination

生殖细胞发育

单细胞多组学

Sex determination in the mammalian gonad involves coordinated lineage decisions in both germ cells and gonadal supporting cells. To define the regulatory programs driving these processes, we generated

NIAID Data Ecosystem00

Normal breast scDNA-ATAC coassay sequencing dataset. Normal breast scDNA-ATAC coassay sequencing dataset

单细胞多组学

乳腺上皮细胞表观遗传

In this dataset, we applied high-throughput nanowell single cell DNA-ATAC co-assay sequencing to profile copy number alterations and chromatin accessibility in 31,176 epithelial cells isolated from br

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An integrative single-cell multiomics profiling of human pancreatic islets identifies T1D associated genes, regulatory regions, and single nucleotide polymorphism

单细胞多组学

1型糖尿病关联研究

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

NIAID Data Ecosystem00