LXR agonism promotes T cell effector chromatin landscapes upon crosspriming by dendritic cells.

Here, we assess chromatin accessibility profiles of OT-I CD8+ T cells upon co-culture with antigen-pulsed BMDCs in the presence or absence of the synthetic LXR agonist RGX-104. Overall design: ATAC-seq of OT-I CD8+ T cells after co-culture with BMDCs in absence or presence of a synthetic LXR agonist.