Human SMG1-9 kinase complex bound to a SMG1 inhibitor
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Human SMG1-9 kinase complex bound to a SMG1 inhibitor Descriptor: 1-[4-[4-[2-[[4-chloranyl-3-(diethylsulfamoyl)phenyl]amino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methyl-urea, ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... Authors: Langer, L.M, Conti, E. Deposit date: 2021-10-06 Release date: 2021-12-01 Last modified: 2025-10-01 Method: ELECTRON MICROSCOPY (3.59 Å) Cite: Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8. Elife, 10, 2021
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2021-10-06
