Crystal Structure of KPT-8602 bound to CRM1 (E582K, 537-DLTVK-541 to GLCEQ)
收藏Protein Data Bank Japan2023-10-18 更新2026-03-21 收录
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Crystal Structure of KPT-8602 bound to CRM1 (E582K, 537-DLTVK-541 to GLCEQ) Descriptor: (2R)-3-{3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}-2-(pyrimidin-5-yl)propanamide, Exportin-1, GTP-binding nuclear protein Ran, ... Authors: Baumhardt, J.M, Chook, Y.M. Deposit date: 2020-06-24 Release date: 2021-01-27 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.193 Å) Cite: Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia. J Hematol Oncol, 14, 2021
创建时间:
2020-06-24



