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Crystal structure of the catalytic core of human DNA polymerase alpha in ternary complex with an RNA-primed DNA template and aphidicolin

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Protein Data Bank Japan2024-02-28 更新2026-03-21 收录
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Crystal structure of the catalytic core of human DNA polymerase alpha in ternary complex with an RNA-primed DNA template and aphidicolin Descriptor: (3R,4R,4aR,6aS,8R,9R,11aS,11bS)-4,9-bis(hydroxymethyl)-4,11b-dimethyltetradecahydro-8,11a-methanocyclohepta[a]naphthale ne-3,9-diol, DNA polymerase alpha catalytic subunit, DNA template, ... Authors: Baranovskiy, A.G, Babayeva, N.D, Suwa, Y, Gu, J, Tahirov, T.H. Deposit date: 2014-04-17 Release date: 2014-11-26 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.52 Å) Cite: Structural basis for inhibition of DNA replication by aphidicolin. Nucleic Acids Res., 42, 2014
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2014-04-17
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