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Co-Crystal Structure of Akt1 in Complex with Covalent-Allosteric Akt Inhibitor 6

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Protein Data Bank Japan2025-10-01 更新2026-04-19 收录
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Co-Crystal Structure of Akt1 in Complex with Covalent-Allosteric Akt Inhibitor 6 Descriptor: ACETATE ION, RAC-alpha serine/threonine-protein kinase, ~{N}-methyl-6-[4-[[4-[2-oxidanylidene-6-(propanoylamino)-3~{H}-benzimidazol-1-yl]piperidin-1-yl]methyl]phenyl]-5-phenyl-pyridine-3-carboxamide Authors: Landel, I, Mueller, M.P, Rauh, D. Deposit date: 2021-02-10 Release date: 2021-09-08 Last modified: 2025-10-01 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Cellular model system to dissect the isoform-selectivity of Akt inhibitors. Nat Commun, 12, 2021
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2021-02-10
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