Targeting Taxane-Platin Resistant Lung Cancers with JumonjiC Lysine Demethylase Inhibitors (ChIP-Seq)
收藏NIAID Data Ecosystem2026-03-10 收录
下载链接：
https://www.ncbi.nlm.nih.gov/sra/SRP075479
下载链接
链接失效反馈官方服务：
资源简介：
Characterization of histone 3 lysine 4 and lysine 27 trimethylation changes upon development of taxane-platin drug resistance in NSCLC cells and evaluation of these histone modifications after treatment with Jumonji KDM inhibitors, JIB-04 and GSK-J4. Overall design: Comparison of H3K4me3 and H3K27me3 profiles between H1299 Parental cells (chemo-sensitive) and H1299 T18 cells (taxane-platin resistant), and assessment of Jumonji KDM inhibitors on H1299 T18 cells (JIB-04 treated vs DMSO treated, and GSK-J4 treated vs. DMSO treated).
创建时间：
2017-09-17
