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Targeting the MKK7–JNK (Mitogen-Activated Protein Kinase Kinase 7–c-Jun N‑Terminal Kinase) Pathway with Covalent Inhibitors

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NIAID Data Ecosystem2026-03-10 收录
下载链接:
https://figshare.com/articles/dataset/Targeting_the_MKK7_JNK_Mitogen-Activated_Protein_Kinase_Kinase_7_c-Jun_N_Terminal_Kinase_Pathway_with_Covalent_Inhibitors/7752200
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资源简介:
The protein kinase MKK7 is linked to neuronal development and the onset of cancer. The field, however, lacks high-quality functional probes that would allow for the dissection of its detailed functions. Against this background, we describe an effective covalent inhibitor of MKK7 based on the pyrazolo­pyrimidine scaffold.
创建时间:
2019-02-21
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