Crystal structure of human BRM in complex with compound 16
收藏Protein Data Bank Japan2023-10-11 更新2026-03-21 收录
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Crystal structure of human BRM in complex with compound 16 Descriptor: ISOPROPYL ALCOHOL, Maltose/maltodextrin-binding periplasmic protein,Probable global transcription activator SNF2L2, N-(5-amino-2-chloropyridin-4-yl)-N'-(4-bromo-3-{[3-(hydroxymethyl)phenyl]ethynyl}-1,2-thiazol-5-yl)urea Authors: Zhu, X, Kulathila, R, Hu, T, Xie, X. Deposit date: 2018-08-17 Release date: 2018-10-31 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.98 Å) Cite: Discovery of Orally Active Inhibitors of Brahma Homolog (BRM)/SMARCA2 ATPase Activity for the Treatment of Brahma Related Gene 1 (BRG1)/SMARCA4-Mutant Cancers. J. Med. Chem., 61, 2018
创建时间：
2018-08-17
