Salivary microRNA expression data from malignant pleural effusion patients and healthy controls

Malignant pleural effusion (MPE) is a common medical problem caused by multiple malignancies especially lung cancers and always along with a poor therapeutic outcome. We investigate the characteristics of salivary microRNAs (miRNAs) of MPE patients and healthy controls, identifying the distinct classes of up-regulated and down-regulated miRNAs during this process Salivary supernatant from 3 MPE patients and 3 healthy controls were collected for RNA extraction.The miRNA profiles of these saliva were detected using the Affymetrix® GeneChip® miRNA 4.0 Arrays (Affymetrix, Santa Clara, CA) for miRNA biomarker signatures discovery.