PD-1 independent of PD-L1 promotes glioblastoma growth through the NF𝜅B pathway
收藏NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE160417
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资源简介：
we found that a proportion of human and murine brain tumor-initiating cells (BTICs) expressed programmed cell death protein (PD-1) in situ and in culture. PD-1 signaling through NF𝜅B promotes BTIC proliferation. Human BTICs isolated from three GBM patients were transfected to overexpresss (OE) PD-1. Cells transfected with vector control were considered as OE control. Transfected cells (OE and OE controls) were subjected to bulk RNA sequencing.
创建时间：
2021-11-30
