Inhibition of microbiota-dependent TMAO production attenuates chronic kidney disease in mice
收藏NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE163276
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Methods: RNA-seq analysis was performed on mouse kidney samples isolated from female apoEKO mice on 4 diets for 14 weeks: (1) Control diet, (2) control + iodomethylcholine (IMC), Control + IMC. IMC is a TMA-lyase inhibitor to prevent TMA production by gut mRNA profiles of apoEKO mouse kidneys fed various diets to determine whether a bacterial TMA lyase inhibitor, iodomethylcholine (IMC), can prevent chronic kidney disease induced by adenine feeding.
创建时间：
2021-01-19
