We used microarrays to detail the global programme of gene expression underlying cellularisation and identified distinct classes of up-regulated genes during this process. Keywords: tissue profiling O
The 18 gene RAS scores, and KRAS/BRAF/NRAS mutation status for 54 CRC samples (15 “bad” samples are in bold; PC1: the first principal component; PC2: the second principal component; 1 = mutation prese
Background: The KRAS gene is mutated in about 40% of colorectal cancer (CRC) cases, which has been clinically validated as a predictive mutational marker of intrinsic resistatnce to anti-EGFR inhibito