QSAR-ready data for progesterone receptor (PR) agonists (source: qHTS assay, PubChem AID 1347036) with 208 RDKit 2D descriptors

This dataset is derived from PubChem BioAssay AID 1347036, titled "Progesterone receptor (PR) small molecule agonists, qHTS assay: Summary". The original assay is part of the Tox21 program and measures activation of progesterone receptor (PR) signaling using a beta-lactamase reporter assay in HEK293 cells engineered with a PR-responsive reporter system. Original dataset statistics: - Tested compounds: 7,671 - Active (agonists): 117 - Inactive: 7,408 RDKit descriptors was calculated with RDKit python package version 2022.9.5