Infection with metacyclic L. major parasites results in significantly higher arginase activity in the lesions of BALB/c mice than CBA mice.

Groups of BALB/c and CBA (n = 4) mice were infected with metacyclic L. major parasites in one hind footpad and 1, 4 and 6 weeks post infection, individual footpads were harvested and arginase activity was determined by enzymatic assay. Values given are the average arginase activity ±standard deviation. Data show the results of one representative experiment out of three independent experiments.