File S1 - In-Depth Characterization of microRNA Transcriptome in Melanoma

Contains: Figure S1. Flow chart for small RNA library construction, sequencing controls, false discovery rate (FDR) and clustering of melanoma specimens and cell lines. Flow chart shows small RNA capturing, amplification and multiplex sequencing (A). Unsupervised clustering of four technical replicates – cultured primary melanocytes from an individual with medium skin color (CMELM) demonstrated a nearly identical miRNA expression pattern between each control (B). Choosing the top-40 miRNAs as classifiers resulted in (DOCX)