Nanoscale Dynamics of Enhancer-Promoter Interactions during Exit from Pluripotency

This Zenodo repository contains data generated for our manuscript. It contains: fig1.csv: Color/shift corrected, pairwise enhancer-promoter coordinates [µm] and distances [µm], in naive and primed mouse embryonic stem cells (mESCs), measured with a spinning disk confocal microscope. Related to Fig 1. fig2.csv: Multiway enhancer-promoter coordinates [µm] and distances for promoters with all their enhnacers [µm], in naive and primed mESCs, measured with a STED mircoscope. Related to Fig 2 D-G and Supplementary Fig S9. fig3.csv: Coordinates [µm] and distances between the promoter [µm] (Nanog or Dppa3), its closest ehnacer and closest intron RNA, in naive mESCs, measured with a STED microscope in confocal mode. Related to Fig 3 and Supplementary Fig S10 C. figS10.csv: Coordinates [µm] and distances between the Nanog promoter [µm], its 3 enhancers (-5, -45, +60) and closest intron RNA, in naive mESCs, measured with a STED microscope. Related to Supplementary Fig S10 D. region_coordinates_mm9.bed: Target names (promoters and enhnacers by the distance from their promoter) and the coordinates of the probed genomic region in mm9.