A large number of cloned cells were established to reveal the allele types in the genome-edited cell population. The editing outcomes were analyzed by multiplex amplicon sequencing of NGS libraries pr
NGS Single cell genotyping of human hematopoietic stem cells isolated from patients with myeloproliferative neoplasms and normal controls, in parallel with single-cell RNA-sequencing using TARGET-seq.
The outputs of Souporcell analysis on the single-cell data from different developmental time points and maternal diabetes conditions. Genotypes are numbered 0-7 (totaling 8) for each sample (maternal
Cancer is a heterogeneous disease, and patient-level genetic assessments can guide therapy choice and impact prognosis. However, little is known about the impact of genetic variability within a tumor,