five

Comprehensive single cell RNA-seq datasets of mice tracheas in 4 time points from E11.5 to E14.5

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE301414
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To explore the molecular signatures of tracheal cells during tracheal development, we performed single cell RNA-seq of developing whole tracheas. We identified 18 cell clusters that constitue trachea tissue. Using sub-clustering analysis of chondrocyte progenitors at E12.5, we found Wnt-responsive chondrocytes that higly express wnt signaling target genes such as Lef1, Notum, Axin2. Transcriptomic analyses at single cell resolution of mouse tracheal cells in 4 time points (E11.5, E12.5, E13.5 and E14.5)
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2025-08-28
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