TCR Clonal Expansions and Oligoclonality of T Cells Infiltrating AAA Lesions.

Figshare2019-07-16 更新2026-04-29 收录

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TCR Clonal Expansions and Oligoclonality of T Cells Infiltrating AAA Lesions.

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2019-07-16

Innate-like T cell subset commitment in the murine thymus is independent of TCR characteristics and occurs during proliferation

T细胞发育

T细胞受体谱系

we compare the TCR repertoires of MAIT1 and MAIT17 cells from the mouse thymus using 5’ scRNAseq and scTCRseq of MR1:5-OP-RU tetramer positive thymocytes. A thorough analysis of TCR features between M

NIAID Data Ecosystem120

Parallel T-cell cloning and deep sequencing of the transcripts of human MAIT cells reveal stable oligoclonal TCRÃ repertoire

T细胞受体谱系

MAIT细胞免疫研究

Mucosal-associated invariant T (MAIT) cells are abundant in humans and recognize conserved bacterial antigens derived from riboflavin precursors, presented by the non-polymorphic MHC class I-like mole

NIAID Data Ecosystem80

TCR repertoire of ankylosing spondylitis patients

T细胞受体谱系

强直性脊柱炎机制

This study was aimed to search for AS-specific T cell receptor (TCR) variants, to determine the phenotype and involvement of corresponding T-cells in joint inflammation.

NIAID Data Ecosystem60

NGS data of T-cell receptor repertoire of naive CD4 and CD8 T-cells in healthy donors

T细胞受体谱系

免疫组库分析

sequence data of 18 healthy donors (TCRbeta repertoire) and 5 healthy donors (TCRalpha repertoire. See Klarenbeek et al. PLOS ONE 2015 (accepted):Somatic variation of T-cell receptor genes strongly as

NIAID Data Ecosystem80

ROR𝛾t directs upregulation of RAG gene expression in DP thymocytes and serves as a multi-faceted regulator of the Tcra repertoire.. ROR𝛾t directs upregulation of RAG gene expression in DP thymocytes and serves as a multi-faceted regulator of the Tcra repertoire.

T细胞发育

T细胞受体谱系

Naik et al. show that RAG gene upregulation in DP Thymocytes is controlled by DPASE, a DP-specific open chromatin region in RAG locus. Reduced RAG expression in DPASE KO mice result delayed and incomp

NIAID Data Ecosystem70

TCR Clonal Expansions and Oligoclonality of T Cells Infiltrating AAA Lesions.

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