five

Pre-neoplastic somatic mutations including MYD88L265P in lymphoplasmacytic lymphoma

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NIAID Data Ecosystem2026-03-13 收录
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https://www.omicsdi.org/dataset/ega/EGAS00001005656
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Normal-cell counterparts of solid and myeloid tumors accumulate mutations years before disease onset; whether this occurs in B-lymphocytes prior to lymphoma remains uncertain. In this study, we sequenced multiple stages of the B-lineage in elderly individuals and patients with lymphoplasmacytic lymphoma, a singular disease for studying lymphomagenesis because of high-prevalence of mutated MYD88.EGA study EGAS00001005656
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2021-11-08
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