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FKBP12 in complex with the BMP potentiator compound 10 at 1.00A resolution

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Protein Data Bank Japan2024-01-24 更新2026-03-21 收录
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FKBP12 in complex with the BMP potentiator compound 10 at 1.00A resolution Descriptor: (1~{R},9~{S},12~{S},13~{R},14~{S},17~{R},18~{E},21~{S},23~{S},24~{R},25~{S},27~{R})-17-ethyl-25-methoxy-12-[(~{E})-1-[(1~{R},3~{R},4~{R})-3-methoxy-4-oxidanyl-cyclohexyl]prop-1-en-2-yl]-13,19,21,27-tetramethyl-1,14,23-tris(oxidanyl)-11,28-dioxa-4-azatricyclo[22.3.1.0^{4,9}]octacos-18-ene-2,3,10,16-tetrone, CADMIUM ION, CHLORIDE ION, ... Authors: Kallen, J. Deposit date: 2020-03-25 Release date: 2021-03-10 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1 Å) Cite: Phenotypic screen identifies calcineurin-sparing FK506 analogs as BMP potentiators for treatment of acute kidney injury. Cell Chem Biol, 28, 2021
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2020-03-25
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