Biological activity of 3-(thiophen-2-yl)pyridine derivatives with diversification at the 4-position of the thiophene core.

aGiven are mean values of at least two independent experiments, S.D. 50 value below 1 µM towards Dyrk1A are marked by an asterisk. Percent values indicate the percentage of inhibition at 5 µM if not stated otherwise (other test concentrations are indicated in brackets).